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J Jonathan Cohen

A First-in-human, Dose Escalation and Dose Expansion Study of SAR445877 in Adult Participants With Advanced Solid Tumors

This is a Phase 1/2, open label, multiple cohort study to assess the safety and preliminary efficacy of SAR445877 as a monotherapy for participants aged at least 18 years with advanced unresectable or metastatic malignancies. The study will include 2 parts: A dose escalation Part 1: for finding the recommended …

18 - 100 years of age Both Phase 1/2
U US GSK Clinical Trials Call Center

A Study on the Immune Response and Safety of Vaccine Against Respiratory Syncytial Virus (RSV) Given to Adults 18 to 49 Years of Age at Increased Risk for Respiratory Syncytial Virus Disease, Compared to Older Adults 60 Years of Age and Above

The aim of this study is to demonstrate the immune response and to evaluate safety of the RSVPreF3 OA investigational vaccine in non-immunocompromised adults 18-49 years of age (YOA), who are at increased risk (AIR) for respiratory syncytial virus (RSV) disease, compared to older adults (OA) (>=) 60 YOA and …

18 - 100 years of age Both Phase 3
L Lisbeth Larsen, PhD

Home-based E-biking Intervention Among Adolescents With Cerebral Palsy

Investigation of the feasibility of virtually group-based e-biking training at home. Twenty young individuals aged 13-25 years with CP (Cerebral Palsy) with a Gross Motor Function Classification System score of 1-3 are recruited for a 12-week home-based e-biking training program.

13 - 60 years of age Both Phase N/A
B Bart Rijnders, MD PhD

Detection of Azole Resistance Inducing Mutations on DNA Extracted Directly From Serum or Plasma of Immunocompromised Patients With an Invasive Aspergillus Infection Azole Resistance PCR Optimalization-study

Invasive aspergillosis (IA) is the most common mould infection in immunocompromised patients with haematological disease. Voriconazole, a triazole, improves overall survival of patients with an IA and is the mainstay of therapy. Resistance of A. Fumigatus emerged as an important clinical problem and infections with azole resistant Aspergillus have a …

18 - 100 years of age Both Phase N/A

Study of [177Lu] Lu-XT033 Injection in Patients With Metastatic Prostate Cancer

This was a multicenter, open-label, phase I/II study to evaluate the safety and tolerability, radiation dosimetry and pharmacokinetic characteristics, and efficacy of [177Lu] Lu-XT033 injection in patients with metastatic prostate cancer, including a phase I study and a phase II extension study.

18 - 80 years of age Male Phase 1/2
M Megan MacDonald, PhD

Multi-site Animal Assisted Intervention for Children With DD and Their Family Dog

The study purpose is to evaluate a novel multidisciplinary approach to fostering a therapeutic partnership between the participants with developmental disabilities and the participants family dog. This will culminate in an Animal Assisted Intervention aimed at increasing activity levels, enhancing social support, and increasing feeling of responsibility and wellbeing within …

10 - 17 years of age Both Phase N/A

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.