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ABTECT-1 - ABX464 Treatment Evaluation for Ulcerative Colitis Therapy -1
This is a multicenter, randomized, placebo controlled study to evaluate the efficacy and safety of ABX464 given at 25 or 50 mg QD in inducing clinical remission in subjects with moderately to severely active ulcerative colitis who have inadequate response, no response, a loss of response, or an intolerance to …
A Study to Understand the Effect of Multiple Ascending Doses of PF-07293893 in Healthy Adult Participants
This study has four parts: Part A, Part B, Part C, and Part D. The purpose of Part A of this study is to learn about the: safety, tolerability, how PF-07293893 is processed by the body when multiple doses of PF-07293893 are given to healthy participants. The purpose of Part …
Efficacy of Exercise Snacks in Real-World Settings in Individuals Living With Type 2 Diabetes
To conduct a pilot randomized control trial to determine the feasibility of a 12-week, technology-enabled exercise snacks intervention in adults living with type 2 diabetes in a real-world setting. We will also assess preliminary efficacy based on measures of glycemic control and fitness.
The Hip Fracture Surgical Approach Trial
The HIFSAT study will compare the standard direct lateral approach to hemiarthroplasty to a new muscle sparing approach (SPAIRE) in femoral neck fracture patients.
Coach to Fit Weight Loss Intervention for Individuals With Serious Mental Illness
This project addresses obesity in the population with SMI by evaluating a weight management program that is not only evidence-based, it is sustainable, transportable, appealing to patients, easy to use, and minimally burdensome to the healthcare system. This effort addresses two HSR&D priority areas: 1) Mental Health: Testing new models …
A Phase 3 Study in Dry Eye Disease
The objectives of this study are to compare the efficacy and safety of tanfanercept ophthalmic solution 0.25% and 1.0% to vehicle for the treatment of DED.
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